Arimidex dosage bodybuilding

Arimidex dosage bodybuilding DEFAULT

GP Anastrozole at Juicehunters

July 26, 2012 (Newswire.com) - Arimidex is not medically recommended for use in body builders or for the treatment of any medical disorder in men. All the data about Arimidex on body builders has been empirically derived by trial and error.

One of the chief reasons why Arimidex is used by body builders is to decrease the side effects which usually occur after the use of other anabolic steroids. The majority of anabolic steroids will cause breast enlargement, loss of hair and water retention. Arimidex with its ability to block the synthesis of estrogen can alleviate some of these embarrassing and obvious side effects of anabolic steroids. Plus, it has been observed that the 1mg dose of Arimidex can also increase the levels of testosterone. In the past, most body builders used drugs like Nolvadex or Proviron against the excess estrogen, but many prefer Arimidex because its actions are rapid and effective. Individuals who use Arimidex for this purpose suggest a starting dose of 0.25 mg/day. Only if no response is seen after a few months, should the dose be increased to 0.5-1.0 mg. The great thing about Arimidex is that it can be used with a variety of anabolic steroids.

However, a word of caution. Anyone who takes Arimidex should get routine measurements of the estrogen levels in the blood. Complete suppression of estrogen can lead to decreases in HDL (good cholesterol). And this can lead to premature development of heart disease.

Anastrozole is compared to Nolvadex (tamoxifen nitrate) as these two drugs are purposely for the reduction of estrogenic activity in the body to halt or delay the progression of cancer. However, Anastrozole is reportedly a more effective drug in combating estrogen-related concerns. This is because as an aromatase inhibitor it blocks the aromatase enzyme, thereby preventing the production of estrogen. Nolvadex, on the other hand, only hinders the action and not the production of this hormone. This is why Anastrozole is considered as the second-line defense against breast cancer. When advanced breast cancer has progressed following treatment of Nolvadex, Anastrozole is usually prescribed. In cases of advanced breast cancer in postmenopausal women, however, Anastrozole is approved for initial use rather than as a second-line defense.

For those male bodybuilders who use steroids, Anastrozole can be effective drug in combating excess estrogen. It is usually taken with Nolvadex to ensure estrogen-related side effects are avoided. If used with such drugs as Propecia (finasteride), it results to more ideal outcome. With Anastrozole preventing estrogen production and with finasteride preventing testosterone conversion to DHT (dihydrotestosterone), you have an efficient duo in eliminating these hormones (estrogen and DHT) undesirable effects, as far as bodybuilding is concerned. Propecia is a specific inhibitor of the 5a-reductase, the enzyme responsible in testosterone conversion to DHT. Propecia reduces the serum concentration of DHT and thereby reduces unwanted androgenic effects like male pattern baldness.

In studies that have been done, Arimidex has been shown to reduce estrogen in the body by roughly 50%. This is a good balance for bodybuilders , because some estrogen is needed in order for the full anabolic benefits of the steroids being taken to be achieved. These results are typically the same with a dosage of .5 mg a day as they are with a dosage of 1 mg a day, meaning that in most cases, a half tablet a day will be sufficient for estrogen control throughout cycle.

Typically, bodybuilders using GP Anastrozole will begin taking it the day they start their cycle, and will run it throughout the duration of steroid administration. It is also important to point out GP Anastrozole's ability to increase testosterone in the body. Some studies have shown that natural testosterone levels have increases as much as 60% after the use of this substance for 7 days. Because of this, bodybuilders find this drug extremely effective during PCT where as they are trying to elevate natural levels as much as possible in order to avoid a post cycle "crash".

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Noah Thomas' tattooed biceps are almost 18 inches around, to hear him tell it. His YouTube channel is full of advice for other weight lifters on how to build muscle. In at least one video, he demonstrates how he injects testosterone.

In another, Thomas talks about a side effect of having too much testosterone: high estrogen levels. Too much of this "female" hormone could lead to a host of well-known problems among bodybuilders -- gynecomastia, low sex drive.

But Thomas -- whom we couldn't reach for comment -- has a plan for fixing that.

"I heard Arimidex is useful," he says in the video. "I don't think I'm going to get any support from my endocrinologist. ... I do think my psychiatrist might be willing to get that for me."

Arimidex, also known by its chemical name anastrozole, is an aromatase inhibitor -- a breast cancer drug. While steroids and growth hormone make headlines when athletes abuse them, breast cancer drugs are a lesser-known staple of doping regimens, for athletes and "weekend warriors" alike. Star therapies of the breast oncology world -- like tamoxifen (Nolvadex) and exemestane (Aromasin) -- provide an easy, non-injectable means of cutting estrogen's unwanted side effects.

And bodybuilders are packing other little-known pharmaceuticals into their routines -- some of which, like ghrelin mimetics and selective androgen receptor modulators (SARMs), are still under investigation in clinical trials and are not available on any regulated market.

Demand for Breast Cancer Drugs

Weightlifters don't seem to have a preference for either class of anti-estrogens. There are the selective estrogen receptor modulators (SERMs) like tamoxifen, or the aromatase inhibitors like anastrozole. Both classes mitigate the effects of estrogen, which is metabolized from testosterone. When testosterone levels are high, estrogen levels also tend to increase as a natural byproduct.

"All they do is block estrogen," Fred Rowlett, president of the North American Natural Bodybuilding Federation, said of the nonchalant attitude weight lifters have about taking cancer drugs. "When you don't have estrogen, you gain nothing but muscle."

Rowlett's organization champions drug-free bodybuilding, and prescription anti-estrogens are on the group's list of banned substances, modeled on that of the International Olympic Committee. These breast cancer drugs are also on the prohibited performance-enhancing drugs lists from the U.S. Anti-Doping Agency and the World Anti-Doping Agency.

Abuse of breast cancer drugs isn't limited to top athletes. "Weekend warriors" and enthusiastic gym-goers are driving demand, as scores of YouTube videos attest. There are no data on how widely used anti-estrogens are in this community, but Rowlett says it's common practice.

Given that they're prescription drugs, the obvious question is how bodybuilders are getting their hands on them.

Rowlett says family practice physicians tend to write the scripts directly to those who are working out. There is also the potential for doctor shopping if one clinician refuses, as Thomas pointed out in his video.

And, of course, there's an underground market that anyone with Internet access can peruse. On its homepage, HardcorePeptides.com boasts tamoxifen and exemestane for under $40. Anti-Estrogens.com is a bit pricier, at $79 for a 30-pack of tamoxifen tablets.

It's unclear if the products are diverted, or if they're synthesized in a homegrown lab, à la Breaking Bad. Some may simply be scams to obtain credit card information, a common problem that many of the sites denounce and attempt to reassure potential buyers with customer service hot lines and other security measures.

A spokesperson for AstraZeneca, which makes Nolvadex and Arimidex, told MedPage Today that diversion and counterfeiting of its products for this purpose "isn't something we're aware of." Pfizer, maker of Aromasin, didn't comment on whether they were aware of the diversion or counterfeiting of the drug.

Then there are the specialized supplements -- which don't require a prescription -- that claim to target estrogen and aromatase, readily up for sale on Amazon.com and other sites. But like the rest of the unregulated supplement industry, there's no guarantee that these bottles contain what's on their labels.

Hungry for the Hunger Hormone

Researchers have been interested in ghrelin, called the hunger hormone for its ability to spark appetite, as a potential target for obesity treatment, but it's had more practical application in wasting disease. Ghrelin mimetics, such as GHRP6 and GHRP2, are still only in clinical trials, and none are commercially available on any market anywhere in the world.

They're readily for sale, however, on a vast amount of websites, along with other growth-hormone-releasing peptides such as ipamorelin and hexarelin. Ghrelin mimetics' potent stimulation of growth hormone secretion is the reason it's valued in muscle-building circles.

The hormones are all blatantly listed on sites like peptideboys.com and deboralabs.com, side-by-side with anabolic steroids and other performance-enhancing drugs. Some purport to be selling their peptides to scientists, but at the same time they tout "discreet shipping."

Jose Garcia, MD, PhD, of Baylor College of Medicine, who has been involved in studies of ghrelin mimetics, told MedPage Today that scientists would never acquire their active drugs that way.

"You would never go to a site like this because there is no quality control so you never know if these products are contaminated or if they contain what they're supposed to," Garcia said. "Not even for animal experiments."

It's likely that these drugs are being made in underground labs, he added.

The same goes for nonsteroidal selective androgen receptor modulators (SARMs), which are also still under investigation for wasting disease. A Google search of where to buy one of the most popular ones, enobosarm (Ostarine is the proposed trade name), returns plenty of results. As with ghrelin mimetics, most of the sites claim their products are for research purposes only and aren't intended for human consumption.

What's Regulated?

Since steroids make the Drug Enforcement Agency's list of controlled substances, inventive entrepreneurs have tried to get around legal issues by making supplements, prohormones, and designer steroids. There's much overlap between these categories, with prohormones being hormone precursors that can amplify the effect of existing hormones, while designer steroids are typically anabolic drugs that were never marketed for medicinal purposes.

Companies that produce these agents have been linked to top athletes, like Barry Bonds and BALCO, and, more recently, Biogenesis and several top baseball players including Alex Rodriguez and Ryan Braun.

Every now and then the FDA also cracks down on these agents -- typically after adverse event reports, as was the case with last month's consumer warning on the Mass Destruction supplement. A 28-year-old in North Carolina developed liver failure after weeks of using the product, which the FDA said contained at least one synthetic anabolic steroid.

Federal prosecutors have also gone after distributors of these supplements, with Bodybuilding.com -- the "largest Internet retailer of supplements in the world," according to a Department of Justice press release -- paying a $7 million fine in 2012 for selling drugs that were misbranded as supplements.

The feds had behind them the Designer Steroid Control Act, which updated the earlier Anabolic Steroid Control Act in order to bring these supplements under the umbrella of illegal steroids.

But anti-estrogens, ghrelin mimetics, and SARMs aren't included in any of that regulation, and they're not on the controlled substances list.

Joseph Moses, a spokesperson for the DEA, told MedPage Today that even though these drugs aren't controlled substances, they could be used in prosecution.

"If we seized them when we seized steroids that are controlled, we could bring them into court as evidence that the individual intended to use those substances or, if it's on a bulk level, to distribute them," Moses said.

Doctors who help weightlifters to obtain steroids via prescription can get in trouble with the law for illegal distribution, as was the case for a Pittsburgh Steelers doctor who falsely claimed his patients had hormonal disorders so they could get their drugs. He was also charged with healthcare fraud -- which covered the drugs prescribed to combat the side effects of steroid use.

Guidelines from both the American Association of Clinical Endocrinologists and The Endocrine Society state that testosterone therapy should be limited to men with testosterone deficiency. The American Academy of Family Physicians also has a policy statement against helping patients obtain performance-enhancing drugs.

"Our policy is very clear," Reid Blackwelder, MD, president of the AAFP, told MedPage Today. "We don't think anything should be prescribed for enhancing athletic performance," including prescription drugs that work against estrogen, he said.

"All of these medicines," he said, "should only be used for their intended medical purposes."

Sours: https://www.medpagetoday.com/primarycare/exercisefitness/43839
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Dosage for Arimidex: What You Need to Know

Overview

If you’re looking into treatment for certain types of breast cancer, your doctor might suggest Arimidex (anastrozole) as an option for you.

Arimidex is a prescription drug that’s used to treat certain types of breast cancer in adult females* who’ve gone through menopause. Specifically, Arimidex is prescribed in some cases for the following types of breast cancer:

This article describes dosage for Arimidex, including its form and strength. It also explains how to take the drug. To learn more about Arimidex, see this in-depth article.

Note: This article covers Arimidex’s typical dosages, which are provided by the drug’s manufacturer. But when using Arimidex, always take the dosage that your doctor prescribes.

* In this article, we use the terms “female” and “male” to refer to someone’s sex assigned at birth. For information about the differences between sex and gender, see this article.

Breast cancer term definitions
  • “Early” means that the cancer hasn’t spread beyond your breast or the lymph nodes in your armpit.
  • “Advanced” means that the cancer has spread into areas of your body near your breast or the lymph nodes in your armpit.
  • “Metastatic” means that the cancer has spread outside of areas near your breast or the lymph nodes in your armpit.

What is Arimidex’s dosage?

Below, you’ll find information about the dosage of Arimidex that’s typically prescribed.

What is Arimidex’s form?

Arimidex comes as a tablet that you swallow.

What strength does Arimidex come in?

Arimidex is available in one strength: 1 milligram (mg).

What are the typical dosages of Arimidex?

The information below describes dosages that are commonly used or recommended. But be sure to take the dosage your doctor prescribes for you. They’ll determine the best dosage to fit your needs.

Dosage for early breast cancer and for advanced or metastatic breast cancer

The typical Arimidex dosage is the same for early breast cancer and for advanced or metastatic breast cancer. This dosage is one tablet (1 mg) taken by mouth once daily.

Is Arimidex used long term?

In some cases, yes, Arimidex may be used as a long-term treatment. How long you’ll take Arimidex for depends on why you’re using it. If you and your doctor determine that Arimidex is safe and effective for you, you might use it long term.

Use for early breast cancer

Arimidex can be used after you’ve already had surgery to remove the breast cancer. When prescribed for this purpose, Arimidex is typically used until the cancer spreads or comes back.

Use for advanced or metastatic breast cancer

When used to treat advanced or metastatic breast cancer, you’ll take Arimidex for as long as your doctor recommends. In studies, when used for this purpose, Arimidex was typically taken for 5 years.

Frequently asked questions

Here are answers to some common questions about Arimidex dosage.

Is there an FDA-approved Arimidex dosage used for bodybuilding?

No, there isn’t an Arimidex dosage for bodybuilding that’s approved by the Food and Drug Administration (FDA).

Arimidex is prescribed to treat certain types of breast cancer in adult females who’ve gone through menopause. The drug works by lowering estrogen levels in the body.

However, some bodybuilders use Arimidex to lessen side effects from anabolic steroids. Anabolic steroids are a human-made form of a hormone called testosterone. Bodybuilders may use these drugs in cycles (starting, stopping, and restarting their use). They’re used as a form of testosterone replacement therapy (TRT) to help muscles grow.

This type of steroid use can cause an increase in estrogen levels. In males, higher estrogen levels can cause gynecomastia (breast growth in males). When used with testosterone, Arimidex offsets the increase in estrogen levels. This helps prevent breast growth in males.

However, the FDA hasn’t approved Arimidex for use while bodybuilding, and it’s illegal to buy Arimidex for this purpose. You shouldn’t take Arimidex without a prescription from a healthcare provider. And you shouldn’t use the drug for conditions it hasn’t been prescribed to treat.

If you have questions about approved uses for Arimidex, talk with your doctor.

Will my dosage of Arimidex change if I take it with other drugs to treat my breast cancer?

It’s not likely. Depending on the type of breast cancer you have, you might use Arimidex with other drugs. But your Arimidex dosage will probably stay the same.

For advanced or metastatic breast cancer, Arimidex is typically used with targeted therapies. Targeted therapies work to attack cancer cells while causing little harm to healthy cells. Examples of targeted therapies include trastuzumab (Herceptin) and pertuzumab (Perjeta).

You may also use other drugs to help manage the side effects of Arimidex. For example, osteoporosis (weakened bones) is a common side effect of the drug. So, your doctor may prescribe drugs such as risedronate (Actonel) or alendronate (Fosamax) to help protect your bones.

For more information about using Arimidex with other drugs, read this in-depth article. And if you have questions about using Arimidex with other breast cancer treatments, talk with your doctor.

What if I miss a dose?

If you forget to take your daily dose of Arimidex, take your missed dose as soon as you remember. But if it’s almost time to take your next dose, skip your missed dose. Then, take your next dose at your usual time. You shouldn’t take any extra doses of Arimidex to make up for a missed dose.

If you’re not sure if you should take or skip your dose, ask your doctor or pharmacist.

If you need help remembering to take your dose of Arimidex on time, try using a medication reminder. This can include setting an alarm, downloading a reminder app, or setting a timer on your phone. A kitchen timer can also work.

What factors can affect my dosage?

The dosage of Arimidex you’re prescribed may depend on certain factors. The main factors that could affect your dosage are the type and severity of the breast cancer you’re using Arimidex to treat.

Your doctor will consider these factors when determining the most appropriate dosage for you.

How is Arimidex taken?

Be sure to take Arimidex exactly as your doctor prescribes.

Arimidex comes as a tablet you’ll swallow. Your doctor will likely have you take your Arimidex dose once per day.

The drug can be taken at any time of day. But, if possible, it’s best to take your dose at the same time each day. This helps keep a consistent amount of the medication in your body at all times.

You can take Arimidex with or without food.

What should be done in case of overdose?

Don’t use more Arimidex than your doctor prescribes. Doing so can lead to serious side effects.

What to do in case you take too much Arimidex

Call your doctor right away if you think you’ve taken too much Arimidex. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.

What should I ask my doctor?

The sections above describe the typical dosage provided by the drug manufacturer. If your doctor recommends Arimidex for you, they’ll prescribe the dosage that’s right for you.

Remember, you shouldn’t change your dosage of Arimidex without your doctor’s approval. Only take Arimidex exactly as prescribed.

If you have questions or concerns about your current dosage, talk with your doctor. Here are examples of questions you may want to ask your doctor:

  • Should my dosage change if I eat certain foods while taking Arimidex?
  • Does my dosage of Arimidex need to change if I’m taking certain other drugs along with it?
  • How long will Arimidex keep working for me after I’ve stopped taking the drug?

If you have breast cancer, you can subscribe to Healthline’s online newsletter. This resource provides helpful information and inspiring personal stories.

Ask a pharmacist

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

Sours: https://www.healthline.com/health/drugs/arimidex-dosage
Aromatase inhibitors

 

Arimidex and its particular uses and properties have been previously outlined. It is used in a variety of different ways within the medical establishment for the treatment of various ailments, with female post-menopausal breast cancer being the primary established indication for Arimidex treatment. However, the context that an anabolic steroid using athlete or bodybuilder is slightly different, and this is what any anabolic steroid user is most concerned with: the proper Arimidex doses for Estrogen control, how to utilize Arimidex doses, and the different manners in which Arimidex doses can be used.

It must first be understood that Arimidex is an aromatase inhibitor, with a wide variety of application in terms of Estrogen control. As an aromatase inhibitor, it holds the ability to exert control over literally all of the potential Estrogenic side effects that anabolic steroid users attempt to avoid or eliminate. The standard protocol (or general rule) for the use of all aromatase inhibitors should be the following:

Attempt to avoid the use of aromatase inhibitors at all costs unless absolutely necessary. If the use of an aromatase inhibitor is necessary, utilize it only when required, and attempt the lowest possible dose for the purpose of Estrogen control rather than Estrogen elimination.

This is extremely important and must be remembered by all readers investigating the use of aromatase inhibitors. The fact of the matter is that the use of aromatase inhibitors, whether it be the three primary AIs (Arimidex, Aromasin, and Letrozole) or any others, will exert negative effects on the body if utilized when they are either unneeded, or when they are utilized too much at Arimidex dosages that are too high.

Remember that the reason for the use of an aromatase inhibitor should at all times be for the purpose of Estrgen control rather than Estrogen elimination, as the complete and total reduction of all Estrogen levels in the body can and does result in deleterious effects on the human body. This will be further explained in the side effects portion of this profile, but a general description is that these compounds (aromatase inhibitors) deprive the body of a very important hormone (Estrogen) that is important for various essential bodily functions at normal physiological levels.

Medical Arimidex Dosage

Within the medical establishment, Arimidex is primarily utilized as an adjunctive drug for the treatment of post-menopausal female breast cancer whereby Estrogen is the prime culprit and aggravator. Prescription Arimidex dosages in such instances are 1mg daily indefinitely until the progression of breast cancer has ceased

Arimidex Dosages During Anabolic Steroid Use

Arimidex in particular cannot be categorized into the three tiers of users (beginner, intermediate, and advanced) as normally outlined and listed in common profiles of the different compounds and drugs. This is due to the fact that Arimidex is an ancillary drug not particularly used for the purpose of performance enhancement, but instead is utilized to combat or mitigate various Estrogen-related side effects when aromatizable anabolic steroids are utilized. In some instances, Arimidex doses might possibly also be utilized to increase the endogenous Testosterone secretion in men, which allows this compound to be utilized as an ancillary medication during PCT (Post Cycle Therapy) phases following the end of an anabolic steroid cycle, but its use on its own for this purpose is not very common and is unlikely to produce noticeable performance enhancing effects.

For the purpose of Estrogen control during a cycle: Arimidex can be effectively utilized to reduce levels of circulating Estrogen in the body during a cycle involving the use of aromatizable androgens (anabolic steroids that have an affinity to bind to the aromatase enzyme and undergo aromatization into Estrogen). Arimidex dosages for this purpose cover a very wide range, and how much Arimidex is required how often is also largely dependent on the doses of aromatizable anabolic steroids used, the individual’s sensitivity to aromatase inhibitors, and the rate of aromatization of the anabolic steroids used. With this being said, the general range of Arimidex doses are 0.5 – 1mg daily. There is much leeway when it comes to this, as each individual should slowly adjust their dose depending on how they feel the body is responding. Even 0.5mg daily is too much for many anabolic steroid users, and often times the recommended dose is actually 0.5mg every other day of Arimidex. These Arimidex doses can easily be adjusted if the user feels it is not working well enough, or if it is reducing Estrogen levels too much.

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Always remember that the idea with the use of aromatase inhibitors is to control Estrogen levels and bring them back to normal physiological levels as opposed to the complete reduction and/or elimination of them, which will cause problems in the body.

Female Arimidex Dosages

Female anabolic steroid users seldom need to worry about rising Estrogen levels, but for those that are competitive bodybuilders that must eliminate the water retention associated with Estrogen that causes the unwanted bloating, the use of an aromatase inhibitor such as Arimidex might be necessary. It is important to remember that medically, Arimidex is approved for use in post-menopausal females only, who possess a very different shift in hormone levels compared to pre-menopausal females. Because medical data has suggested that Arimidex is far more effective in females than males (80% average reduction in Estrogen versus 50% respectively), Arimidex doses of 0.5mg daily should suffice and in fact often times become too much, in which case the individual might feel the need to adjust to 0.5mg every other day or even 0.5mg once every two days.

Arimidex Dosage for Increased Endogenous Testosterone Secretion and PCT (Post Cycle Therapy)

It has been previously mentioned that Arimidex use has been shown to raise the endogenous production of Testosterone levels in men. This is through the negative feedback loop of the HPTA (Hypothalamic Pituitary Testicular Axis), whereby it has been found that excess Estrogen in men can and does suppress the output of endogenous Testosterone, leading to hypogonadism[1]. Arimidex in particular in many studies has demonstrated to hold the capability to raise Testosterone levels through the reduction of Estrogen. One particular study evaluated 12 males that were administrated with Arimidex doses of 0.5mg and 1mg for 10 weeks, and the study concluded that, among various hormonal alterations due to Arimidex administration, there was a 58% increase in serum Testosterone levels in the test subjects[2]. In this study, LH (Luteinizing Hormone) and FSH (Follicle Stimulating Hormone) had also increased, which are the two important gonadotropins that signal the testes to begin production of Testosterone.

One can easily conclude, based on the data provided, that Arimidex should be an effective addition to the necessary increases in Testosterone required during the post-cycle weeks following cessation of anabolic steroid use. There is one issue with the addition of Arimidex in a PCT program that includes the use of SERMs such as Nolvadex and Clomid, which are known as absolutely essential components to a PCT program. The problem is that Arimidex and Nolvadex both directly counteract one another. One study has demonstrated that when Arimidex is utilized with Nolvadex, Nolvadex will decrease blood plasma concentration of Arimidex (as well as Letrozole, another commonly used aromatase inhibitor)[3].

The conclusion here is that the use of Arimidex and Nolvadex together is a very bad idea. Therefore, Arimidex’s use as a PCT component is very limited if used in conjunction with Nolvadex. Instead, its use with HCG might be more beneficial, but this also presents the problem of the essential component of a SERM for the purpose of endogenous Testosterone stimulation being absent. Therefore, a better aromatase inhibitor choice for PCT instead of Arimidex would be Aromasin (Exemestane), because unlike Arimidex, Aromasin has it has not been demonstrated have its effectiveness eliminated by Nolvadex as shown in studies[4].

Proper Administration and Timing of Arimidex Dosages

There are no special considerations with administration of Arimidex doses, and it can be taken at any time of the day (morning, night time, before, during, or after meals).

One important note to make with Arimidex is that a full week (7 days) is required before blood plasma levels of Arimidex have reached its optimal peak level, although its half-life is approximately 48 hours[5].

Expectations and Results from Arimidex Dosages

Arimidex will reduce Estrogen levels by a great deal in individuals, and Arimidex users must be cautious to ensure that these Estrogen levels do not plummet too low to be considered healthy. As Estrogen levels reduce, the physique may take on more of a harder ‘grainier’ and ‘ripped’ look due to the loss of water retention provided by Estrogen. This results in very little to no subcutaneous fluid, which will present the underlying musculature more prominently. The one exception to the issue of complete Estrogen elimination is in competitive bodybuilders that require almost total elimination of water retention on the competition day. In such a situation, an aromatase inhibitor such as Arimidex might be utilized by a competitive athlete at higher doses only days leading up to a competition for the physique altering reasons previously stated. Near-total reduction of Estrogen should not be maintained for more than a 48 hour period for health reasons.

 

 

 

Medical References:

 

[1] “Dangers of Excess Estrogen In the Aging Male”. Faloon, William. Life Extension Magazine, November 2008.

[2] Estrogen suppression in males: metabolic effects. Mauras N; O’Brien KO; Klein KO; Hayes V. J Clin Endocrinol Metab 2000 Jul;85(7):2370-7   (ISSN: 0021-972X)

[3] Comparative clinical pharmacology and pharmacokinetic interactions of aromatase inhibitors. Boeddinghaus IM, Dowsett M. J Steroid Biochem Mol Biol. 2001 Dec;79(1-5):85-91.

[4] Inhibitory effect of combined treatment with the aromatase inhibitor exemestane and tamoxifen on DMBA-induced mammary tumors in rats.

[5] Pharmacology and pharmacokinetics of the newer generation aromatase inhibitors. Buzdar AU. Clin Cancer Res. 2003 Jan;9(1 Pt 2):468S-72S.

Sours: https://www.steroidal.com/anti-estrogens-pct/arimidex/arimidex-dosage/

Bodybuilding arimidex dosage

femara

Active: Letrozole/Anastrozole

Overview and History of Arimidex

Arimidex belongs to a category and class of drugs known as aromatase inhibitors (AIs). Aromatase inhibitors belong to an even broader class of drugs known as anti-estrogens. The other subcategory of drugs under the anti-estrogens category is known as selective estrogen receptor modulators (SERMs), such as Nolvadex and Clomid. AIs and SERMs make up anti-estrogens. Aromatase inhibitors differ greatly from SERMs in their actions and how they deal with the issues of estrogen control. The misunderstanding that SERMs, such as Nolvadex and Clomid, serve to lower estrogen levels must first be addressed.

This is a persistent rumor among the bodybuilding community that has begun to erode as of late. SERMs serve to block the action of Estrogen at the receptor sites in breast tissue. Estrogen, therefore, cannot exert its effects there through the receptor. SERMs will also act as Estrogens at receptor sites in other cells throughout the body, liver, for example. SERMs do not lower circulating levels of Estrogen in blood plasma. Aromatase inhibitors do this by eliminating the production of Estrogen. It disables the aromatase enzyme responsible for the estrogen conversion (or aromatization) of androgens into Estrogen.

History

Zeneca Pharmaceuticals (now AstraZeneca) developed Arimidex as an aromatase inhibitor. synthesized and designed to treat female patients suffering from advanced breast cancer. FDA approval came in 1995 and they released it onto the American prescription drug market. Arimidex is as viewed as one of the newer aromatase inhibitors, known as a third-generation aromatase inhibitor. The reason why both aromatase inhibitors and SERMs act to block Estrogen’s effects in different ways. They found that estrogen stimulates and accelerates the majority of breast cancers.

Arimidex is used among breast cancer treatments as an adjunct treatment. This refers to an additional treatment when other standard treatments have failed to meet proper expectations. Before the development and release of Arimidex as a breast cancer treatment medication, the primary medication used for treatment for decades prior was Nolvadex (Tamoxifen). Nolvadex is the standard treatment for breast cancer patients. When Nolvadex treatment cannot meet expectations during breast cancer treatment, second-line adjunct drugs such as Arimidex are used.

Further Studies

They did one such study on Arimidex with over 9,000 post-surgery female breast cancer patients. It observed its efficiency compared to Nolvadex (both alone and both together), resulting in far more favorable outcomes for Arimidex over Nolvadex. The study in 2002 concluded that Arimidex was far more effective at cancer regression. Increasing the survival rate of breast cancer patients following treatment. It was then this study (and others) prompted interest among the anabolic steroid community. They began investigating the benefits of its effects on strong Estrogen levels suppression.

A later study showed the risk of recurrence of breast cancer reduced by 40% with Arimidex use. However, patients experienced an increase in bone fractures. Maintenance of proper mineral retention reduces because of low estrogen levels caused by Arimidex use.

A first for bodybuilders

Because Arimidex was the very first aromatase inhibitor for many bodybuilders to have taken notice of, it is the most popular aromatase inhibitor used among anabolic steroid users for Estrogen control. Used with anabolic steroids by athletes for the control of almost all Estrogen-related side effects such as gynecomastia, water retention and bloating, rising blood pressure (because of water retention increases from Estrogen).

This is in contrast with SERMs such as Nolvadex, which only block gynecomastia. Studies have shown that Arimidex use in males has is very effective. Reduction of circulating Estrogen blood plasma levels by as much as 50% at only a dose of 0.5 – 1mg daily. This is a considerable decrease in men.  It is still much lower than the 80% reduction observed in female breast cancer patients. However, there are significant differences between the sexes.

Aside from the use in bodybuilders, Arimidex has also had uses in males. Males who exhibit high levels of Estrogen use Arimidex to combat these ailments. Arimidex has been used to treat male adolescents that exhibit excessive Estrogen levels during puberty, resulting in unwanted pubertal gynecomastia. Excessive Estrogen levels in adolescent males can cause stunted growth. This is because Estrogen plays a key role in fusing the growth plates of the bones shut, preventing any further linear growth.

Chemical Characteristics of Arimidex

Arimidex is a non-steroidal aromatase inhibitor. This is to say that it does not possess the characteristic four ring cycloalkane ring carbon structure common of all types of steroids.

Properties of Arimidex

Arimidex’s effects on serum Estrogen level control can be quite drastic even at a dose of 1mg daily. Over 80% of patients showed estrogen reduction. Arimidex can be so effective at inhibiting the aromatase enzyme and thereby reducing Estrogen levels that this compound is typically only administered to post-menopausal females, and/or utilized when other first-line treatments for breast cancer has failed.

Arimidex and Letrozole are both classified as non-steroidal and non-suicidal aromatase inhibitors. They both compete with the substrate for binding to the enzyme active site. This is very different from Aromasin (Exemestane). A sterodial and suicidal aromatase inhibitor that acts as a mechanism-based steroidal inhibitor. It mimics the substrate and is converted by the enzyme to a reactive intermediate. This deactivates the aromatase enzyme.

Aromasin’s chemical structure resembles the traditional points that bind to Testosterone. It essentially ‘fools’ the aromatase enzyme into binding with it, only to become inhibited/deactivated. Because the binding strength is so great, this inhibition becomes permanent for the aromatase enzyme. Arimidex and Letrozole, being non-suicidal aromatase inhibitors, both compete with the enzyme’s traditional ‘targets’ rather than being assured a permanent spot (which is the advantage that Aromasin has over the other two).

Bodybuilders and athletes utilizing anabolic steroids will usually favor aromatase inhibitors such as Arimidex for its ability to eliminate rising Estrogen levels at its root cause: aromatase. By disabling the aromatase enzyme, levels of androgens that can aromatise (such as Testosterone, Dianabol, etc.) cannot convert into Estrogen, thereby eliminating any possible risk of Estrogen-related side effects.

Arimidex Side Effects

Arimidex (Anastrozole) is an ancillary compound for Estrogen control in the body. Male users generally tolerate it well. There are, however, some Arimidex side effects that cause concerned. This primarily exists in the form of excess reduction of blood plasma levels of Estrogen in the body, as well as long-term Estrogen suppression. Arimidex does affect females in a far greater and significant manner than it does in male users as well.

When it comes to Estrogen reduction and suppression, it must be understood that unlike SERMs (Selective Estrogen Receptor Modulators) such as Nolvadex or Clomid (Clomiphene Citrate), Arimidex belongs to the family of aromatase inhibitors. This means that it serves to disable the aromatase enzyme, which is responsible for the aromatization – or, conversion – of Testosterone into Estrogen. In other words, Arimidex reduces total circulating Estrogen levels at the root source as opposed to SERMs, which serve to merely block the activity of Estrogen at select receptor sites.

Studies have demonstrated that Arimidex use results in the increased incidence and probability of experiencing bone fractures. Although this is a more female-specific side effect of Arimidex use, Estrogen does play an important role in the promotion and retention of bone mineral content in males as well. Studies conducted discovered that Arimidex negatively impacts calcium turnover levels in bone tissue. Even with short term use.

Most Common Side Effects

We commonly associate lethargy and fatigue with Arimidex use. As with nearly all Estrogen reduction compounds, a reduction in circulating Estrogen levels means that the important role that Estrogen plays in the CNS (Central Nervous System) is reduced, thus resulting in possible instances of chronic fatigue. This results from Estrogen levels being reduced. These levels are far too low to be healthy.

One particularly prominent side effect of Arimidex use is the negative impact on blood cholesterol profiles. As with nearly all Estrogen reducing compounds, Arimidex will also decrease HDL (good) cholesterol and increase LDL (bad cholesterol). This is because Estrogen is responsible for the promotion of healthy cholesterol levels in the body. Disruption of normal blood plasma levels of Estrogen will indeed throw that off. The more severe the reduction of Estrogen, the more severe the cardiovascular impacts.

The possibility of an Estrogen rebound is an important sided effect. This exists in particular with two of the three most popular aromatase inhibitors (Arimidex and Letrozole). The third aromatase inhibitor, Aromasin (Exemestane) does not share this same attribute of the possibility of Estrogen rebound. This is because unlike Aromasin, Arimidex is a non-suicidal aromatase inhibitor. This means that Arimidex will bind with and disable the aromatase enzyme, but it does not do it permanently. At some point, Arimidex will dissociate with the enzyme and the enzyme will then be free to do its job again in the body. This means there is the risk of Estrogen levels rebounding (and thus, Estrogen related side effects) if you halt Arimidex use to soon.

Dosing and Administration of Arimidex

Arimidex (Anastrozole) treats post-menopausal female breast cancer where the primary cause is Estrogen. The dosage of Arimidex in these cases call for 1mg taken once per day until the progression of cancer has stopped.

Arimidex For Gynecomastia and Estrogen Control On-Cycle

Use 0.5 – 1mg per day for control of Gynecomastia and Estrogen while on a cycle. The user can adjust this depending on tolerance and reaction to the compound. Everyone should adjust their Arimidex dosage according to their response. It is not uncommon for 0.5mg/day to even be too much (or too little) for some. Remember that the purpose here is Estrogen control during a cycle, not total elimination of Estrogen levels.

Arimidex For Post Cycle Therapy (PCT)

Studies have shown that Arimidex can assist in endogenous natural Testosterone production in males. A dosage of 0.5mg to 1mg per day should be sufficient for the duration of any PCT length.

It possesses a half-life of approximately 48 hours. Blood plasma level peak only after 7 days of consistent use. You can take it at any time of day, with or without food.

Estrogen Elimination Dangers

Attempt to avoid the use of aromatase inhibitors at all costs unless necessary. If the use of an aromatase inhibitor is necessary, utilize it only when required. Attempt the lowest possible dose for Estrogen control rather than Estrogen elimination.

It is of importance to readers investigating aromatize inhibitors. The use of aromatase inhibitors, like the three primary AIs (Arimidex, Aromasin, and Letrozole), have serious negative effects on the body. Especially when used when not needed, or used too often.

The reason for the use of an aromatase inhibitor should always be for Estrogen control rather than elimination. The complete and total reduction of all Estrogen levels in the body results in serious effects in the human body.

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Sours: https://www.anabolicreview.co.za/arimidex/
NOLVADEX: Fastest Way To DESTROY Any BODYBUILDING CYCLE

Should bodybuilders be taking Arimidex?

Arimidex is a treatment for breast cancer that some bodybuilders take to reduce the side effects of anabolic steroids. The drug lowers estrogen levels in the body.

Bodybuilders who take anabolic steroids to try to increase muscle mass and improve athletic performance can experience a range of symptoms. In some cases, males might start to grow breasts due to an increase in estrogen levels.

Arimidex lowers estrogen levels and can prevent breast growth in males. However, the drug also has side effects of its own.

In this article, we discuss what Arimidex does, why bodybuilders might use it, and the possible side effects.

How it may work for bodybuilding

Arimidex is the brand name for anastrozole. Doctors may the drug to postmenopausal women with certain types of breast cancer.

Arimidex stops aromatase from working in the body. Aromatase is an enzyme that makes estrogen from steroid hormones, including testosterone. By doing this, it lowers the amount of estrogen in the body.

People who use anabolic steroids for bodybuilding can experience a range of .

These drugs disrupt hormone production in the body and may increase estrogen. Higher levels of estrogen can cause males to develop gynecomastia, which is the enlargement of the breast glands.

By reducing estrogen levels, Arimidex could prevent gynecomastia in males taking anabolic steroids.

Side effects

Arimidex can cause several side effects by disrupting hormone production in the body. For example, lower estrogen levels can lead to the thinning and weakening of bones.

Some other common side effects :

  • joint pain
  • nausea and vomiting
  • hot flashes
  • weakness
  • tiredness

It is possible to have an to Arimidex, which can cause:

How should you take Arimidex?

Arimidex comes as a small tablet for oral use only. The tablets are usually 1 milligram in size.

The Food and Drug Administration (FDA) have only approved Arimidex for use in cancer treatment. There are no formal guidelines for its use in bodybuilding.

The FDA guidelines for breast cancer suggest a typical dosage of one tablet per day, but a doctor may prescribe a different dosage, depending on the case.

Taking Arimidex for bodybuilding is not recommended. Many of the side effects of anabolic steroids usually go away after a person stops using them. Estrogen levels should return to normal, and gynecomastia should reduce.

Other uses

The primary use of Arimidex is to treat breast cancer. It may be part of treatment for postmenopausal women with:

  • Early hormone receptor-positive (HR+) breast cancer. Arimidex can lower the risk of cancer returning or spreading following surgery.
  • Advanced or metastatic HR+ or HR-unknown breast cancer. It is not usually possible to treat these cancers using surgery, so doctors may prescribe Arimidex as a first-line treatment.
  • Advanced or metastatic breast cancer that returns following initial treatment with tamoxifen (Nolvadex). Arimidex is a second-line treatment in these cases.

Sometimes, treatments for other types of cancer, such as ovarian cancer, might include Arimidex. However, the FDA only recommend its use for breast cancer.

Alternatives

Several other drugs — typically, those for the treatment of breast cancer — lower estrogen levels in the body.

For example, other aromatase inhibitors, such as exemestane (Aromasin), and a class of drugs called selective estrogen receptor modulators (SERMs) that act on estrogen receptors. Doctors may use SERMs to treat breast cancer, female infertility, and dyspareunia.

Although these drugs may lower estrogen levels, the FDA do not recommend that people take them for bodybuilding purposes.

Several natural products may also play a role in lowering estrogen levels, although there is limited scientific evidence to confirm their effectiveness. These include:

  • wild nettle root
  • grape seed extract
  • chrysin
  • maca

Male vs. female

Arimidex is primarily for breast cancer treatment, and most of the research relates to postmenopausal women.

Estrogen plays a more significant role in the bodily function of females than males. Lowering estrogen levels can, therefore, have a more serious effect on females.

For this reason, female bodybuilders should avoid taking Arimidex or any other drug that lowers estrogen levels.

When to see a doctor

It is best to consult a doctor before taking any drug that disrupts normal hormone production.

Some people may be taking other medications or have medical conditions that affect hormone levels. Taking Arimidex could cause more serious issues in these cases.

It is essential to stop taking the drug and see a doctor right away if there are signs of an allergic reaction, such as swelling or rashes.

Summary

Some bodybuilders use Arimidex to control gynecomastia, which is a side effect of taking anabolic steroids. It causes males to grow breasts.

Arimidex can have several side effects and is usually a treatment for breast cancer. It is not advisable for people to take Arimidex for bodybuilding.

It is best to speak to a doctor before taking any drugs that may affect hormone levels.

Read this article in Spanish.

Sours: https://www.medicalnewstoday.com/articles/arimidex-bodybuilding

Now discussing:

Androgenic anabolic steroids, also known as AAS, are very common amongst people that lift weights and are looking to bulk up and build muscle.

To build muscle, an individual must be very committed to their cause, as noticeable muscle growth does not happen overnight.

Training naturally, it can be months before you begin to notice any real differences to your physique, and that’s assuming that you lift regularly and have your anabolic diet on point.

Training naturally might be safer, but you can certainly see why natties get frustrated.

They bust their butts in the gym, training harder than ever, along with prepping their meals, spending heaps on meat and supplements, and they barely have anything to show for it several weeks down the line.

More frustratingly still, is the fact that somebody using gear will jump on cycle, and will literally transform their physique in a matter of weeks, surpassing said natty in every way possible.

More and more lifters are being tempted to cross over to the dark side and use steroids, but they do so at their own risk.

PCT after a steroid cycle is vital, which is why we’re looking at what is Arimidex PCT today.

PCT is often overlooked after a cycle ends, and the results could be devastating.

Legal Disclaimer:

Anabolic steroids are incredibly dangerous and can potentially be fatal.

We don’t condone their use, nor do we recommend their use.

The simple fact of the matter is that people have always used steroids, despite knowing the risks, and they always do.

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If people insist on using gear, we would much rather they know what they’re doing, which is why we do what we do.

Why Using PCT?

When you use anabolic steroids, you change your body chemistry.

In the simplest explanation possible, steroids are basically synthetic hormones that are all based on testosterone.

Testosterone is an androgenic hormone with anabolic properties, making it perfect for muscle growth.

Steroids basically mimic the effects of testosterone, except for the fact that the effects they provide have been increased exponentially.

Now, when you mess with your body chemistry, strange and dangerous things can happen to your body.

One common issue with steroids is that many of them aromatize and convert to Estrogen, and subsequently cause testosterone in the body to convert to Estrogen too.

Estrogen to a bodybuilder is like Kryptonite to Superman.

Estrogen causes men to suffer from gynecomastia, or gyno, which literally causes them to develop breasts and breast tissue like women.

It also causes water retention, bloating, hormonal imbalances, suppressed testosterone production, complete testosterone production shut down, damage to the major organs, and much more besides.

Doesn’t really make steroids seem that appealing does it?

Well, if you run what is known as Post Cycle Therapy, or PCT for short, you can substantially reduce the risks, dangers, and side effects associated with steroid use.

There are many different drugs and compounds that can be used for PCT when it comes to steroid use, and Arimidex is up there amongst the most popular.

What Is Arimidex PCT?

Arimidex is a drug that belongs to a class of drugs known as AIs.

No, we’re not talking about Artificial Intelligence which is the same AI that has tried and failed to kill Sarah Connor on multiple occasions.

The AIs we’re talking about are Aromatase Inhibitors, like Aromasin!

Here is a case study about Aromasin VS Arimidex.

Arimidex is also known as anastrozole and it is an anti-estrogen drug.

Initially, the drug, like many steroids before it, was developed for medical purposes.

It was originally developed to treat breast cancer in women, particularly in post-menopausal women.

The idea was that, because it essentially blocks the effects of Estrogen, the drug would help treat breast cancer which was stimulated by Estrogen.

Basically, they reduced the amount of Estrogen that the female body was able to produce after a woman had gone through the menopause.

Interestingly, it is still FDA-approved and is still used for medical purposes and can be prescribed by a doctor.

However, as most typical bodybuilders are not post-menopausal women, you might be wondering why you’ll find Arimidex as part of their cycle stack.

Well, the reason for this is because Arimidex can actually be used to help negate the effects of steroids on the body, specifically, those related to increased levels of Estrogen.

It isn’t actually a SERM (Selective Estrogen Receptor Modulator) like some people wrongly believe, but it is still very popular amongst bodybuilders running PCT.

Now, when it comes to PCT, there are two drugs that rule the roost.

Virtually all PCT cycles include at least one of these drugs.

The third-most-popular drug for PCT, however, is the one we’re looking at today.

A common misconception is that these drugs prevent Estrogen from being produced.

They don’t.

What they actually do is block the action of Estrogen in specific Estrogen receptor sites within the body.

As Estrogen is unable to bind to these receptors, it cannot do its damage.

As it is an AI, it works by disabling aromatase enzymes which cause androgens such as testosterone, to aromatize and convert to Estrogen.

What Are The Benefits Of Using Arimidex For Men?

There are many benefits associated with using Arimidex, though primarily we are going to focus on the steroid-related benefits first.

These include, but are not limited to:

1. No gyno

When men use steroids, one common side effect is gyno, or gynecomastia, as it is fully known.

Gyno is a condition that literally causes men to grow and develop breast tissue.

Now, it’s incredibly rare for a man to develop a full of breasts, although that has happened in the past.

What is more likely, however, is that the man in question will experience sore and tender nipples, which begin to swell and go puffy.

Men generally develop puffy nipples and begin to retain fat around their nipples that causes them to look swollen and unaesthetic.

Some people believe that gyno can be cured by simply losing weight and performing chest exercises to tighten and tone up the pecs.

This isn’t true.

Once you suffer from gyno, the only way to cure it is to undergo surgery.

It is rumored that The Rock himself had gynecomastia surgery during his WWF days in the late 90s.

When it comes to the gyno, prevention is the best cure, which is where Arimidex comes so useful.

Gynecomastia is caused when androgens in the body aromatize thanks to aromatase enzymes, causing a man to suffer from female characteristics.

Arimidex is an A.I, so androgens such as testosterone are unable to be converted into Estrogen.

The end result after a steroid cycle is a powerful, lean, and muscular chest that is completely free of any signs of gyno.

https://www.youtube.com/watch?v=v4uTImwfKJg

2. Reduced Acne

When you use steroids, another frequent side effect is acne.

Acne, or ‘backne’ as it is sometimes called because steroid users often experience spotty backs, can really dent your self-confidence.

When men use steroids, they do so because they want to look better and feel better about themselves.

Ironically, however, side effects such as acne can have the opposite effect.

Rather than feeling good about themselves, men actually feel worse because they’re so spotty.

If you remember what happened when you went through puberty, the sudden increase in testosterone caused you to develop spots and pimples.

When you use steroids, the same thing happens.

Arimidex, however, helps you to avoid acne after a steroid cycle.

So, you get to keep your gains, with the added bonus of having smooth and healthy skin.

3. No Water-retention

After bodybuilders finish running a steroid cycle, sometimes, again ironically, they find that their bodies look worse than before.

Sure, they’ve built muscle and they look big, but if they are dealing with a lot of excess Estrogen in the body, this can actually result in another side effect in the form of water retention and bloating.

After using steroids, most bodybuilders want to show off their gains and show off how ripped and vascular they are.

If androgens such as testosterone have interacted with aromatase enzymes however, this can actually result in excess Estrogen which causes the bodybuilder to retain water and look bloated and washed out.

Arimidex, therefore, is great for reducing and preventing water retention and bloating, making it a great drug for showing off those all-important gains.

4. Reduced Blood Pressure

It isn’t just for physical improvements that bodybuilders utilize Arimidex.

It turns out that the drug can also provide health benefits that will help you out internally too, which is crucial.

Too often, bodybuilders focus on how they look, that they forget about what’s going on inside their bodies.

Another very common side effect of steroid use is hypertension, also known as high blood pressure.

Hypertension is known as the ‘silent killer’ because it is a condition that can potentially be fatal, yet there are no obvious signs or symptoms of its presence.

Often, the only time to diagnose hypertension is to have your blood pressure tested by a medical professional.

Hypertension can cause damage to the arteries and blood vessels, it can cause damage to the kidneys, damage to the heart, it can cause blood clots, strokes, cardiovascular disease, and even heart attacks.

Needless to say, hypertension is a condition that nobody wants to suffer.

If you’re looking for just one reason to run Arimidex after your steroid cycle, how about the fact that it can help to significantly reduce and normalize blood pressure and can thereby help you to avoid/cure high blood pressure in the form of hypertension.

5. Restore Testosterone Levels

In some instances of steroid use and abuse, bodybuilders have managed to naturally shut down the production of this hormone in their own bodies.

This happens because the brain detects such elevated levels of testosterone, or what it perceives to be testosterone (steroids are synthetic versions of testosterone) in the body, and it thinks that something is wrong and that the tests are producing too much.

It, therefore, sends a signal to the testes, telling them to stop making testosterone.

It’s kind of like switching the engine off of an overheating car and allowing it to cool down.

When a bodybuilder is on gear, his T-levels are through the roof, so he doesn’t care that his balls are no longer making the hormone.

Once he jumps off-cycle, however, it’s a different story.

Bodybuilders that do not run PCT often have to receive testosterone replacement therapy for the rest of their lives because the tests are unable to start producing the hormone again after being closed down and put out of commission for so long.

PCT in the form of drugs such as Arimidex however, helps to restore your natural hormone production levels.

PCT is like pressing the ‘restore factory settings’ button on your own body.

Arimidex PCT

Arimidex Dosage:

So, we’ve looked at why it’s beneficial and what it is, but now we need to look at how much you should be taking.

Well, this can actually be tricky because the amount you take will depend on which steroid cycle you are running.

If you were running a 6-week Anavar cycle, for example, you would likely need to consume less than if you were running a 12-week Tren, Dianabol, and Test-E cycle.

With that being said, however, there are some general guidelines that most users tend to adhere to.

Each day, ideally you should aim for 0.5mg to 1mg.

Just be wary, that for some, 0.5mg per day is too much, in which case you should go with 0.5mg every other day.

Here, you can gradually increase your dosage slightly, depending on how you feel and whether it appears to be working its magic.

Arimidex Side Effects:

Even though Arimidex PCT is designed to reduce and prevent side effects from steroids, it does generally have a few common side effects of its own, that users need to be wary of.

These include:

  • Headache
  • Nausea
  • Diarrhea
  • Weight gain
  • Sore throat
  • Hot flushes
  • Aching joints
  • Trouble swallowing
  • Tingling of the extremities
  • Hot flushes
  • Elevated cholesterol levels
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